Versione Italiana


Localized lipoatrophy


Dott. Luciano Schiazza
Specialista in Dermatologia e Venereologia
Specialista in Leprologia e Dermatologia Tropicale
c/o InMedica - Centro Medico Polispecialistico
Largo XII Ottobre 62
16121 Genova
cell 335.655.97.70 - studio 010 5701818



Localized lipoatrophy is characterized by noninflamed, focal loss of subcutaneous tissue. The case is that of a young woman with no personal or familial history of any systemic disorder (panniculitis, diabetes mellitus, connective tissue disease), injections of corticosteroids, antibiotics, etc. She presented a bilateral,  band like horizontal  depression of  both thighs. The skin lesions showed no evidence of clinical inflammation. It had never been symptomatic nor had any pigmentary changes.

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She was usued, in her office, to seat on a plastic seat, for hours, crossing her right leg over the left and conversely: the site of indentations on the thighs corresponded exactly to hard border of the seat.

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Prolonged, repeated local pressure to the thighs by the edge of the seat, with a long history of  leg crossing, explained this condition.  Such pressure could result in involution of subcutaneous fat in a similar way to lipoatrophia semicircularis.

This condition is mainly of cosmetic concern only. Lesions had gradually resolved after seat had been changed and leg crossing avoided.